TY - BOOK AU - Silverman,Richard B. AU - Holladay,Mark W. TI - The organic chemistry of drug design and drug action. SN - 9780123820303 (alk. paper) U1 - 615.19 PY - 2014/// CY - Waltham PB - Elsevier KW - Pharmaceutical chemistry KW - Bioorganic chemistry KW - Molecular pharmacology KW - Drugs KW - Design N1 - Introduction -- Lead discovery and lead modification -- Receptors -- Enzymes -- Enzyme inhibition and inactivation -- Dna-interactive agents -- Drug resistance and drug synergism -- Drug metabolism -- Prodrugs and drug delivery systems ER -